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Careers

A Career AT Orphazyme

Orphazyme is a development stage biopharmaceutical company. Our highly motivated and talented team of professionals is dedicated to the development of innovative therapeutic approaches to severe diseases, and cooperates with the research community worldwide.

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Current VacancIES

Director, US Medical Affairs

Position Description
Orphazyme US, Inc. is based in Newton, MA and is a wholly-owned subsidiary of Orphazyme A/S, headquartered in Copenhagen, Denmark. Orphazyme, founded in 2009, is a biopharmaceutical company focused on bringing novel treatments to patients living with life-threatening or debilitating rare diseases. Our research focuses on developing therapies for diseases caused by misfolding of proteins and lysosomal dysfunction. Arimoclomol, the company’s lead candidate, is in clinical development for four orphan diseases: Niemann-Pick disease Type C, Gaucher disease, sporadic Inclusion Body Myositis, and Amyotrophic Lateral Sclerosis. The Denmark-based company is listed on Nasdaq Copenhagen (ORPHA.CO). For more information, please visit www.orphazyme.com.  

Position Summary
The Director, US Medical Affairs will at first report to the CMO and be responsible for defining, developing the medical affairs strategy, and executing the tactical activities for neuromuscular and LSD/metabolic disease areas. The ideal candidate will be a highly self-motivated, collaborative, scientifically-oriented, and accomplished Medical Affairs leader with a flexible, hands-on and team-oriented style. They will provide medical guidance and leadership for the US consisting of medical communications, medical training, and KOL and payer engagement. Key activities will include: Establishing the medical strategy for multiple indication programs, lead execution of relevant medical affairs activities, forging strong relationships with key opinion leaders, supporting payer-related activities, compliantly support pre-commercial activities, and patient advocacy initiatives. The position will be based in the greater Boston area.

Roles and Responsibilities

  • Lead strategy development and execution of medical affairs activities in the US, including medical and payer advisory boards, medical education initiatives, publications planning, diagnostic programs, congress activities, and payer interactions

  • Communicate medical information and key findings externally and within the company

  • Maintain high level of scientific and medical expertise in neuromuscular and LSD/metabolic diseases, serve as key medical resource in the diagnosis, treatment and management of targeted disease areas and associated products

  • Hire and manage the US Medical Affairs team including Rare Disease Medical Liaisons

  • Provide medical expertise to the commercial organization to compliantly assist in the development and execution of commercial activities, including training

  • Serve as the medical reviewer for abstracts, publications, disease-related and product-related promotional materials, and non-promotional scientific materials, including reimbursement dossiers and payer materials

  • Forge strong relationships with key opinion leaders and treaters

  • Initiate and advance collaborations with health care professionals, researchers, payers, patient advocacy organizations

  • Create and lead the execution of medical symposia

Requirements and Qualifications

  • Will thrive in a fast-paced, changing environment with limited structure that requires flexibility, resourcefulness, being efficient, and communicating remotely

  • At least 7 years in biopharmaceutical industry with at least 3 years in Medical Affairs

  • MD or PharmD with a degree  

  • Experience working in rare diseases and in start-up environment highly preferred

  • Medical specialty training optimally in pediatric or adult neurology or relevant drug development experience within the field of pediatric and adult neurology

  • Proven inspiring leadership and people management experience

  • Able to work both independently and as a member of an integrated, interdisciplinary team in being accountable for carrying out assigned responsibilities

  • Articulate in oral, presenting and writing skills, with a demonstrated ability to communicate well with others at varying professional levels, especially medical

  • Able to effectively present information and respond to questions from groups of managers, clients, customers, and the general public

  • Able to think creatively, analyze data, efficiently to define problems, develop solutions, and draw valid conclusions

  • Track record of forming compliant partnerships with commercial colleagues

  • Is responsive and approaches work with a sense of urgency

  • Demonstrates genuine compassion and passion for patients and families

  • Willing and able to travel up to 40% as needed, including some weekends

  • Willing to work from home at first until a US office is opened  

To apply, please send your CV and application to contact@orphazyme.com, att.: Chief Commercial Officer, Paul Merrigan. 

We encourage anyone interested in the job to apply, irrespective of gender, age, race, religion, or ethnicity.

 

 

Director, Global Patient Relations

Position Description
Orphazyme US, Inc. is based in Newton, MA and is a wholly-owned subsidiary of Orphazyme A/S, headquartered in Copenhagen, Denmark. Orphazyme, founded in 2009, is a biopharmaceutical company focused on bringing novel treatments to patients living with life-threatening or debilitating rare diseases. Our research focuses on developing therapies for diseases caused by misfolding of proteins and lysosomal dysfunction. Arimoclomol, the company’s lead candidate, is in clinical development for four orphan diseases: Niemann-Pick disease Type C, Gaucher disease, sporadic Inclusion Body Myositis, and Amyotrophic Lateral Sclerosis. The Denmark-based company is listed on Nasdaq Copenhagen (ORPHA.CO). For more information, please visit www.orphazyme.com.  

Position Summary
The Director, Global Patient Relations is an emotionally intelligent person responsible for building trust, relationships, and mutually beneficial collaborations with multiple professional and patient advocacy organizations primarily in the US and Europe. The person will develop strategy and implement programs that foster advocacy for the patient communities we serve. She/he will be the primary interface with the patient community and contribute to the development and delivery of communications to this vitally important group of stakeholders. They will take the lead in championing the patient’s perspective into the company’s decision-making process and program development. This person will be instrumental in helping to shape and nurture the company’s culture centered around the purpose of addressing the needs of patients and making a meaningful difference in their lives. The position will be based in the greater Boston area.

Roles and Responsibilities

  • Proactively lead the development of the strategic plan and company philosophy around patient advocacy engagement and collaboration
  • Develop and facilitate communications with patient advocacy organizations in collaboration with media and communication plans that enhance corporate reputation
  • Solicit feedback and gain insights from the patient community to ensure their needs are being met and their experience with our company is optimized
  • Serve as the primary point of contact and interface with disease-related patient communities and rare disease umbrella organizations in the US and Europe
  • Develop and deliver messaging to patient advocacy groups for transparent communications related to our company, programs and products
  • Advise on processes related to ensuring the patient perspective is incorporated into all appropriate initiatives including disease education programs, clinical trial recruitment, research collaborations and patient support services
  • Serve as the patient liaison within the company to ensure productive, compliant, and value-added partnerships are in place with the patient organizations
  • Partner and work across functions to identify opportunities and develop and implement alliances with professional and patient advocacy groups.
  • Contribute to the conception, creative development, and pull-through of patient-related initiatives, activities, and community support services, including disease-related educational programs, patient meetings, community service projects, advisory boards, patient speakers, clinical trial awareness, policy, etc.
  • Identify and develop disease advocates for them to tell their stories and advocate for improved health
  • Remain current on new developments in industry, regulatory, legal, policy, and social media areas relevant to interactions with patient communities and organizations
  • Ensure programs are aligned to meet strategic goals while being compliant with industry, legal, and regulatory guidelines in the US and EU
  • Support clinical trials recruitment and market access efforts
  • Build, manage, and create process for the Patient Relations function
  • Create Global Patient Relations budget and manage grants for patient organizations

 Qualifications & Requirements

  • Bachelor’s degree; advanced degree in social work, psychology, nursing, counseling, or related field preferred

  • At least 5 years’ patient relations experience and developing advocacy function in a global biopharma company; experience in rare diseases and a start-up environment is highly preferred;  

  • Can excel in a fast-paced, changing environment with limited structure that requires flexibility, resourcefulness, being efficient, and remote communications

  • Accomplished in dealing with complex human-related issues to develop solution-oriented strategies

  • Demonstrated ability to take action and communicate complex concepts in a simple way to offer solutions, resolve issues, and mitigate risks

  • Proven excellence in trust-building and relationship-building

  • Proven ability to deliver oral, written, presentation communications across different audiences and personalities

  • Success in positively influencing in an objective and diplomatic manner

  • Reputation for being highly perceptive, socially intelligent, genuine, and intuitive

  • Exudes empathy, is an active listener, and has an innate passion for patients/families

  • Approaches work with a sense of urgency and responsiveness

  • Shown to maintain composure in stressful situations and de-escalate conflict

  • Is culturally intuitive, sensitive, and experienced with relating to people in other countries

  • Works collaboratively as a team player and has a track-record of achieving results in a matrix organization

  • Willing and able to at times travel up to 40% in the US and Europe as necessary, including some weekends

  • Willing to work from home at first until a US office is opened

To apply, please send your CV and application to contact@orphazyme.com, att.: Chief Commercial Officer, Paul Merrigan. 

We encourage anyone interested in the job to apply, irrespective of gender, age, race, religion, or ethnicity.

 

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In general, Orphazyme always welcomes uninvited applications. We ask that the following items are included:

  • Curriculum Vitae
  • Your motivation for applying to Orphazyme, and why you are a good match with us
 

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