REPORTING OF TRANSACTIONS IN ORPHAZYME'S SHARES MADE BY PERSONS DISCHARGING MANAGERIAL RESPONSIBILITIES

Copenhagen, Denmark, March 7, 2019 – Pursuant to the Market Abuse Regulation article 19, Orphazyme A/S, CVR no. 32266355 (“Orphazyme”), hereby notifies receipt of information of the following transactions in Orphazyme’s shares by persons discharging managerial responsibilities in Orphazyme:

1 Details of the Reporting Person / Closely Associated Person

a) Name

Anders Hedegaard

2 Reason for the notification

a) Position/status

Member of the Board of Directors

b) Initial notification/Amendment

Initial notification

3 Details of the Company, emission allowance market participant, auction platform, auctioneer or auction monitor

a) Name

Orphazyme A/S

b) LEI code

54930025OZD2GGSQ7L42

4 Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted

a) Description of the financial instrument, type of instrument and identification code

Shares

ISIN DK0060910917

b) Nature of the transaction

Purchase of shares

c) Price(s) and volume(s)

Price (s)

Volume (s)

DKK 47.00

600

DKK 46.80

345

DKK 47.20

439

DKK 47.20

92

DKK 47.15

474

DKK 47.15

55

DKK 46.70

291

DKK 46.90

516

DKK 47.00

518

DKK 46.90

359

DKK 46.90

410

DKK 47.00

53

DKK 47.00

475

DKK 46.90

332

DKK 47.05

451

DKK 47.50

317

DKK 47.40

357

DKK 47.05

5

DKK 47.05

1

DKK 47.05

341

DKK 47.60

221

DKK 47.90

32

DKK 47.90

28

DKK 47.90

4

DKK 47.90

34

DKK 47.90

34

DKK 47.90

28

DKK 47.90

7

DKK 47.90

34

DKK 47.90

35

DKK 47.90

24

DKK 47.90

10

DKK 47.90

35

DKK 47.90

46

DKK 47.90

19

DKK 47.90

27

DKK 47.90

47

DKK 47.90

46

DKK 47.90

7

DKK 47.90

40

DKK 47.85

48

DKK 47.85

47

DKK 47.85

5

DKK 47.85

15

DKK 47.85

195

DKK 47.85

1

d) Aggregated information

  • Aggregated volume

  • Price

Aggregated volume: 7,500

Price: DKK 47.15

e) Date of the transaction

2019-03-07 – between 8:00 and 16:00 UTC-time

f) Place of the transaction

Nasdaq Copenhagen A/S - XCSE